Horehound
Medicinal Uses, Interactions, Side
Effects
Marrubium vulgare-white horehound or
horehound-is a member of the mint family. This wild herb
is indigenous to Europe and Morocco. The woolly, hairy
(hoary) leaves and white flowers have been used in herbal
medicines.
Photo
from Longwood Gardens, by
Raul654. |
Uses and
Benefits:
Horehound is used mainly as an
expectorant and antitussive; it has been employed as therapy
for coughs, bronchitis, respiratory infections, and sore
throats, and used as a tonic. It has also been taken for
cardiac arrhythmias and diabetes; as a bowel and uterine
stimulant; for loss of appetite and flatulence; and externally
for sores and wounds. Horehound is alleged to have antioxidant,
anti-inflammatory, vasodilator, and diuretic
properties.
Horehound may have been used as
a bitter confection or food since ancient times. It was chosen
as one of the bitter herbs (maror) of the Jewish Passover feast
and is still used in confectionary, teas, ales, and other items
as a bitter flavor.
Pharmacology:
White horehound contains
flavonoids (such as quercetin) and diterpenes, including the
lactone premarrubiin which is a precursor of the bitter
marrubiin. It also contains alcohols (e.g., marrubenol,
marrubiol), mucilage, saponins, and the alkaloids betonicine
and stachydine; a number of less important chemicals have also
been identified. It is claimed that marrubinic acid works as an
appetite stimulant and as a choleretic. Horehound, like other
bitter substances, may function as a nonĀspecific expectorant
by stimulating the gastro-pulmonary mucokinetic reflex'y, It
has demonstrated hypoglycemic effects in rabbits; this may
support its use as an antidiabetic medicine in
Mexico.
Clinical
Trials:
There are no clinical trials that
demonstrate the various alleged medical uses of horehound or
its main constituent, marrubiin.
Adverse
Effects:
The herb appears well tolerated
in usual doses. However, some individuals may experience
difficulty with its bitter quality. Large doses cause nausea
and vomiting, and have a laxative effect.
Side Effects and
Interactions:
No drug interactions are
recognized.
Cautions:
It has not been proved to be safe
in pregnancy, but no restrictions are known during
lactation.
Preparations &
Doses:
Horehound can be prepared in
liquid extracts and teas, and is commonly found in tablet form,
such as medicinal candies or throat pastilles. The usual
therapeutic dose is 4.5 g/day of the herb, or 30-100 ml of the
juice; dosing is recommended three times a day.The taste may
need to be disguised to make it palatable.
Summary
Evaluation
Horehound may have minor
expectorant properties since, in with all bitter agents, it may
stimulate the gastropulmonary expectorant reflex. However, it
has not been evaluated dinically, and it cannot be recommended
for serious or persistent spiratory disorders. Other alleged
health benefits lack evidence. Nevertheless, this ancient herb
remains popular for sore throats other minor
conditions.
Peter Thomas is a writer, who
writes many great articles on herbal medicines for common
ailments and diseases. For more information on herbal remedies
and home remedies visit our site on health care
at http://www.health-care-tips.org/
.
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